Human medications lead list of top pet toxins in 2023, data shows

It might not come a surprise in the practice to receive calls about a pet ingesting non-food items, but the critical fact for the veterinary team is whether or not that item is toxic.

In a statement released by the American Society for the Prevention of Cruelty to Animals (ASPCA) Animal Poison Control Center (APCC), data shows the top toxins pets are exposed to. Based on the organization’s total call volume for 2023, human over the counter (OTC) medications top the list for 10 consecutive years, making up nearly 17 percent of the APCC’s calls for the year.

The annual report comes ahead of ahead of National Poison Prevention Week (March 17 – 23) and shares data from more than 400,000 animals the ASPCA APCC helped across 50 states.

“Veterinary experts at the ASPCA Poison Control Center see a steady increase in call volume each year, which reflects an increased recognition of items that pose a potential risk to pets,” says Tina Wismer, DVM, DABVT, DABT, senior director of toxicology, ASPCA Animal Poison Control Center.

Food items come in second on the list, with protein bars and drinks, grapes and raisins, and products with xylitol (e.g. chewing gum) reported to contribute 16.2 percent of the calls. Recreational drugs, such as marijuana-based substances, hallucinogenic mushrooms, and cocaine made the top 10 spot for the second year. These cases received by the APCC involves pets ingesting marijuana-laced baked goods, which are reportedly more dangerous than ingesting plant material and can result in symptoms, such as stomach upset, urinary incontinence, and ataxia.

A list enumerating the top pet toxins of 2023 based on the ASPCA Animal Poison Control Center’s total call volume for the year, with human over-the-counter (OTC) medications and food and drinks as top two.
The ASPCA Animal Poison Control Center’s Top Pet Toxins of 2023 report is based on the organization’s total call volume for the year, which involved helping more than 400,000 animals via their 24/7 hotline. Source: ASPCA APCC

Additionally, the organization reports an increase of 74 percent in calls relating to hallucinogenic mushrooms versus the year prior.

According to Carly Fox, DVM, senior veterinarian in the Emergency & Critical Care Unit of, the Schwarzman Animal Medical Center (AMC) in New York City, there is also a rise of mushroom-related cases in New York City. Further, Dr. Fox says combined toxicities (including mushrooms and chocolate for example) is quite common.

View the full report of the ASPCA Animal Poison Control Center (APCC) Top Pet Toxins of 2023.

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